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Mammalian alkaline phosphatases

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A review and discussion of new knowledge on the structure and function of mammalian alkaline phosphatases (APs) gained over the last 25 years. It covers: * The structure, regulation and expression of the AP genes * The three-dimensional structure of APs and mutagenesis work that further defined the structural/functional domains of the isozymes * The phenotypic abnormalities of the different AP knockout mice * Our current understanding of the in vivo role of the AP isozymes. The book also describes the possible use of APs as therapeutic agents and therapeutic targets and the many uses of these enzymes in clinical medicine and in biotechnology.

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Mammalian alkaline phosphatases, José Luis Millán

Taal
Jaar van publicatie
2006
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(Hardcover)
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Titel
Mammalian alkaline phosphatases
Taal
Engels
Uitgever
Wiley-VCH
Jaar van publicatie
2006
Formaat
Hardcover
Aantal pagina's
337
ISBN10
3527310797
ISBN13
9783527310791
Reeks
Aantekening
A review and discussion of new knowledge on the structure and function of mammalian alkaline phosphatases (APs) gained over the last 25 years. It covers: * The structure, regulation and expression of the AP genes * The three-dimensional structure of APs and mutagenesis work that further defined the structural/functional domains of the isozymes * The phenotypic abnormalities of the different AP knockout mice * Our current understanding of the in vivo role of the AP isozymes. The book also describes the possible use of APs as therapeutic agents and therapeutic targets and the many uses of these enzymes in clinical medicine and in biotechnology.