IARC Scientific Publications - 154: Biomarkers in Cancer Chemoprevention

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The evaluation of potential cancer chemopreventive agents require large, long-term, randomized trials in humans. Biomarkers that would allow the identification of subjects exposed to carcinogenic agents, or of individuals genetically, susceptible to cancer would be of great value. This volume is the product of an attempt to assess current knowledge and experience with the use of biomarkers in cancer chemoprevention. It comprises an expert report on the current state of the art use of biomarkers in cancer chemoprevention, introductory sections covering general topics in cancer chemoprevention, and contributions, directed to biomarkers of exposure, intermediate effect and susceptibility relating to six major cancer sites: skin, colorectum, breast, prostate, liver, and upper aerodigestive tract.