The author's life intertwines the challenges and joys of medicine with the tranquil pursuit of flyfishing. Through personal anecdotes, he explores how both passions have shaped his experiences, offering insights into the fulfillment derived from his profession and recreation. The narrative reflects on the balance between the rigors of medical practice and the serenity found in nature, showcasing a unique blend of dedication and leisure.
This book brings together in one volume fifteen discoveries that have had a major impact upon medical science and the practice of medicine but where the scientists involved have not been awarded a Nobel Prize. Its aim is to publicize the achievements of these lesser-known heroes of our time and thereby inform and entertain the reader, whether medical student, professor or scientifically-minded layman.
Ch. 1. The discovery of insulin / Robert Tattersall -- ch. 2. The discovery of the cure for pernicious anaemia, vitamin B12 / A. Victor Hoffbrand -- ch. 3. The discovery of penicillin / Eric Sidebottom -- ch. 4. The introduction of cardiac catheterisation / Tony Seed -- ch. 5. The discovery of the structure of DNA / James Scott and Gilbert Thompson -- ch. 6. The interpretation of the genetic code / John MacDermot and Ellis Kempner -- ch. 7. The discovery of neuropeptides and radioimmunoassay of peptide hormones / Jaimini Cegla and Stephen Bloom -- ch. 8. The development of computer-assisted tomography / Adrian M.K. Thomas -- ch. 9. The discovery of prostaglandins / Rod Flower -- ch. 10. The antibody problem and the generation of monoclonal antibodies / Herman Waldmann and Celia P. Milstein -- ch. 11. The discovery of the LDL receptor and its role in cholesterol metabolism / Gilbert Thompson -- ch. 12. The invention of the polymerase chain reaction and use of site-directed mutagenesis / Anne K. Soutar -- ch. 13. The discovery of the pathophysiological role of nitric oxide in blood vessels / Keith M. Channon -- ch. 14. The discovery of helicobacter pylori / Chris Hawkey -- ch. 15. The discovery of RNA interference - Gene silencing by double-stranded RNA / Richard P. Hull and Timothy J. Aitman