Deze actievolle serie volgt een groep buitengewone individuen die gezegend zijn met bovennatuurlijke krachten, ontleend aan de literatuur. Duik in een wereld vol mysteries, schimmige organisaties en intense gevechten, waarbij elk teamlid vertrouwt op zijn unieke, door beroemde auteurs geïnspireerde vaardigheid. Het is een verhaal over vriendschap, vastberadenheid en de strijd tegen duistere krachten in het moderne Yokohama, Japan.
Having been kicked out of the orphanage, a despairing young man by the name of Atsushi Nakajima rescues a strange man from a suicide attempt--Osamu Dazai. Turns out that Dazai is part of an armed-detective agency staffed by individuals whose supernatural powers take on a literary bent!
Regaining consciousness after nearly losing his life to Akutagawa, Atsushi is paralyzed by the thought of bringing more death and destruction down on the heads of his companions at the Armed Detective Agency and vows to run away. But before he can make good on his resolution, the Mafia sends Ryuurou Hirotsu of the merciless Black Lizard squad to storm their offices! Between the bomb-tossing Motojirou Kajii and the demure, kimono-wearing Kyouka Izumi, will the Mafia's literary giants close the book on Atsushi and the Armed Detective Agency for good?!
Atsushi has managed to rescue Kyouka Izumi, who's been working as a Port Mafia assassin against her will. But the deadly Akutagawa hasn't given up yet! Atsushi's not the only one with a dangerous foe, however. Mafia member Chuuya Nakahara makes his appearance, and his grudge against Dazai is nothing to sniff at!