Deze verzamelserie brengt uiteenlopende helden uit het Marvel-universum samen die zich verenigen om een nieuwe, dodelijke dreiging het hoofd te bieden. Wanneer een vijand uit het verleden opduikt met plannen om de onderwereld te verenigen, moeten iconische figuren als Daredevil, Luke Cage, Jessica Jones en Iron Fist hun verschillen opzij zetten. Samen worden ze een formidabele kracht die de stad verdedigt tegen de duisternis die haar probeert te verzwelgen.
Daredevil! Luke Cage! Jessica Jones! Iron Fist! Individually, these four heroes have been on the front lines of the battle to keep the streets of the city safe and secure. But now, with a deadly enemy from the dim past making a major move to unite the underworld, they will need to become more... they will need to become...DEFENDERS!
The Defenders - Iron Fist, Jessica Jones, Luke Cage and Daredevil, protectors of the people - are in a desperate struggle to keep New York City safe in the wake of the power vacuum caused by the Kingpin's absence and the all-out street war that results! So what could make things even worse for our team of harried heroes? Would you believe - Deadpool? The Kingpin's kingdom is up for grabs, and the streets of Marvel will burn as every major underworld figure makes a play to be the next kingpin of crime! Unfortunately for them, this is exactly why the Defenders have gathered - to make our streets a safer place! But bad press is about to have a disastrous impact on Luke's and Jessica's lives. And how exactly does Diamondback know so much about the Defenders? COLLECTING: DEFENDERS 6-11