Obesity and the kidney

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We are currently facing an alarming obesity epidemic, which leads to serious health issues such as metabolic syndrome, type 2 diabetes, cardiovascular diseases, certain cancers, musculoskeletal disorders, and pulmonary diseases. Recent evidence indicates that obesity significantly impacts renal structure and function. The adipocyte, a source of various hormones and cytokines, influences renal function beyond just mediating hypertension; it can induce renal diseases like focal segmental glomerulosclerosis and accelerate chronic renal disease progression. This volume is the first comprehensive compilation on this critical topic, featuring discussions on both pathophysiological and clinical aspects from leading experts in the field. It integrates concepts on how obesity affects renal structure and function, reviews the epidemiology of the issue, and offers therapeutic suggestions. This publication is essential for internists, nephrologists, hypertensiologists, cardiologists, and urologists treating patients with obesity-related renal diseases. Additionally, basic scientists such as renal physiologists, pathologists, pharmacologists, biochemists, and epidemiologists seeking a thorough overview of the subject will also benefit from this resource.