Critical contributions of primate models for biopharmaceutical drug development

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The 17th Covance Primate Symposium was held in Münster on April 16 and 17, 2008, with a record attendance of 131 participants from 13 countries and 56 organizations. The focus was on the "Critical Contributions of Primate Models for Biopharmaceutical Drug Development," a timely topic given the rise of biopharmaceuticals, particularly monoclonal antibodies, in preclinical development where nonhuman primates serve as key models. The symposium also addressed changes in environmental conditions for primates in research, particularly in Europe, and their implications for pharmaceutical development. Additional discussions included developmental and juvenile toxicity testing and the potential of stem cell-derived therapeutics. Experts presented on four main topics: the promise of stem cell-derived therapeutics, the European environment for primate research as a potential barrier or opportunity, innovative approaches to developmental and juvenile toxicity testing, and the current challenges faced in biopharmaceutical drug development. Notable contributors included Alexander Breidenbach, Christian Freichel, Werner Frings, and others, reflecting a diverse range of expertise in the field. The demand for research involving nonhuman primates in preclinical development is expected to grow in the coming years.