Derek Gordon Boeken

The collection showcases the diverse poetry of Derek Gordon, affectionately known as Bringwonder the Storyteller, celebrating his life and creative legacy. Compiled by his daughters and a close friend, it features a range of styles from his teenage years to his final works, highlighting his quirky and insightful writing. This tribute not only honors his impact on those around him but also invites readers to experience the depth and breadth of his talent, capturing the essence of a true Renaissance Man.

This special issue celebrates the anniversary of the seminal publication introducing the transmission disequilibrium test (TDT) as a method for testing linkage and association in family data. It features a series of reviews and methodological papers by noted researchers in the field, each of whom has made advances in family-based association testing. Anyone performing family-based association testing and those who wish to learn more about the history regarding the development of the TDT will appreciate the additional investigations of the TDT statistic presented in this issue.

This special issue of Human Heredity discusses a wide range of current topics related to genetic disease association analysis. Topics covered include phenotype definition, genotype-phenotype correlation, and strategies for managing phenotypic data, multipoint methods for genotype error detection, as well as the robustness of genomic control methods for case/control association in admixed populations. Further addressed are the relative costs for different types of genotype errors in genetic model-based association, a comprehensive review of optimal SNP marker selection in disease association, and the comparative information of multiple SNPs and single microsatellites. Anyone involved in complex genetic research, i. e. clinicians, geneticists and statistical geneticists, will find guidance on study design, on how to evaluate phenotypes used in linkage and association findings, and on how to avoid pitfalls that typically arise in genetic studies.