Reviews recent research on how and why such a tiny bit of fluorine (even a single atom) can so profoundly change the pharmacological effect of a compound. The last major summary of the field was published in 1982. Among the materials discussed are antiviral and anticancer compounds, cardiovascular drugs, anesthetics, antibacterial drugs, and central nervous system agents. Reproduced from typescripts. Annotation copyright Book News, Inc. Portland, Or.
