Reference materials in analytical chemistry

Analytical chemistry is vital for decision-making across various fields, including science, economy, health care, and environmental protection. Accurate analytical results are essential, requiring a specified level of uncertainty and comparability, often on a global scale. Reference materials play a crucial role in ensuring these standards are met. The diversification of reference materials is driven by advancements in analytical chemistry, the emergence of new methods, and the inclusion of new analytes and matrices. This growing demand for reference materials leads to an increased need for information and guidance, particularly regarding calibration, validation, and the use of certified reference materials. This handbook serves as a comprehensive resource for analytical chemists and technical personnel in laboratories, aiming to become a standard reference work. It covers topics such as analytical thinking, the demands on analytical chemistry, measures to build confidence, and the classification of reference materials, including definitions, physical characteristics, supplied properties, metrological qualifications, preparation methods, and intended use.