RNA/DNA and Cancer

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In this insightful work, Joseph G. Sinkovics shares his extensive observations of cancer cells in vivo and in vitro. He explores how primordial cell survival pathways within the RNA/DNA complex are endogenously reactivated in multicellular hosts, often masquerading as self-elements or placentas, which the host evolutionarily supports. The author asserts that there is no evidence of “malignantly transformed” human cells surviving in nature, yet in laboratory conditions, these cells thrive and replicate as immortalized cultures, retaining vitality even when stored in liquid nitrogen. He posits the intriguing possibility of an astrophysical environment where such cells could exist, potentially beginning with their exosomes populating that space. These immortal cell populations might persist as individuals or reorganize into multicellular colonies, representing life throughout the Universe's duration. This thought-provoking exploration comes from a disciplined investigator and clinician with a stellar reputation, venturing into a territory few have approached from similar perspectives. It will resonate with researchers interested in cell survival pathways and cancer cell studies.