Rodent malaria: Gender susceptibility to malaria infection

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Focusing on the impact of malaria, this book examines the spleen and liver's roles in combating Plasmodium chabaudi infection through studies on lymphotoxin receptor-deficient mice. It highlights the vulnerability of male LT R-/- mice, which, despite castration or vaccination, are more susceptible to infection compared to wild type male C57BL/6 mice. This research provides insights into the immune response mechanisms and potential therapeutic approaches to address malaria's significant public health threat.