Mast cells

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Mast cells, first described by Paul Ehrlich in 1878, are crucial components of the immune system found in connective tissues, particularly in areas exposed to the environment such as the skin, respiratory system, and digestive tract. Their strategic presence suggests a primary role in initiating defense mechanisms against foreign invaders. Increasingly recognized for their contributions to tissue homeostasis, remodeling, and repair, mast cells are vital for maintaining health, facilitating wound healing, and supporting both innate and adaptive immunity.