FIBROBLAST GROWTH FACTORS

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The fibroblast growth factor (FGF) family is crucial for regulating metabolic and physiological functions across various tissues in vertebrates, influencing tissue homeostasis and responses to injury. Abnormalities in FGF signaling can lead to numerous diseases, including developmental malformations, atherosclerosis, pulmonary hypertension, and cancer. Understanding this signaling system is vital for gaining insights into both healthy and diseased states, and is essential for developing targeted therapeutic strategies for FGF-related conditions.