Late effect of sertraline on experimental depression in rats

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The study explores the effects of neonatal sertraline treatment on body weight, depression, and exploratory behavior in young adult rats. The experimental group received a daily dose of 15 mg/kg of sertraline from the first to the twenty-first day of life, while the control group was administered distilled water. The research aims to understand how early intervention with a selective serotonin reuptake inhibitor influences behavioral outcomes later in life.